Evaluation Prevalence agents of urinary tract infection and antibiotic resistance in patients admitted to hospitals in Hamedan University of Medical Sciences 1391-92

Mohammad Reza Arabestani, Hassan Mahmoudi, Mohammad Alikhani, Saeid Khosravi

Abstract


Background and Objectives: Urinary tract infection is the most common bacterial infections in humans if treatment is not done properly it will have been dangerous consequences. Today, increasing bacterial resistance to antibiotics used in the treatment of diseases of the problems facing medical science. The aim of this study was to investigate the prevalence of antibiotic-resistant bacteria in the urinary tract infections in hospitalized patients learning to be in Hamadan University of Medical Sciences.              

Method: This cross-sectional study-described in the first six months of the year from 1391 to 92 were based on data collected from hospital laboratory data in Hamadan University of Medical Sciences databases. Midstream urine samples obtained from all patients and the McConkey agar and blood cultures after 48 h of cultivation on 105 urine CFU/ml was considered as positive. Antimicrobial susceptibility was done by the standard disk diffusion method (using disks PadtanTeb) and the results were analyzed using the software SPSS.

Results: The most common bacteria isolated including Escherichia coli (72%) and coagulate-negative Staphylococci (10%), Staphylococcus aureus (3%) and the presence of bacteria of the proteus mirabilis (4%) and klebsiella species (6%). The results showed that E.coli isolates resistant to most antibiotics, Cotrimoxazole (74%) and the least resistance to Nitrofurantion (4%) and all isolates were susceptible to Amikacin (100%). Staphylococcus aureusisolates were susceptible to Vancomycin (100%) and the rate of resistant to oxacillin, erythromycin and Clindamycin were over (90%) and also, Proteus spp. was resistant (50%) to Nitrofurantion and ciprofloxacin.

Conclusions: In this study, most causing agents of UTIs belonged to the family ofenterobacteriaceae and determination of antibiotic susceptibility pattern should be considered.


Keywords


Urinary tract infections, Antibiotic resistance, Disk diffusion method, Antimicrobial susceptibility

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